The prefecture of Karditsa is located in the middle part of the Greek mainland, halfway on the national road network connecting Athens with Thessaloniki. The mountainous landscape alternating with the fertile valleys composes the beauty of this region.

Built on the slopes of Kissavos at 260 metres above sea level, the capital Karditsa looks like a beautiful "balcony" commanding a panoramic view over the Aegean Sea. It claims the largest chestnut production throughout Greece, celebrated each October with the "Chestnut Feast". The splendid square of the town, reached through its winding alleyways, has numerous traditional tavernas, a crystal-water spring and wooden benches under the shade of a centuries-old plane tree. The roads and the scenic paths around the town lead to the highest crests on Mt. Kissavos and to the splendid beaches of Platia Ammos, Panagia, Kalibi and Pigadi.

Karditsa is a good destination for year-round vacations, fishing, water sports, walking, climbing, skiing and hunting. While in Karditsa, it is worth taking a trip to Lake Plastira, an artificial lake at 800 metres above sea level, set amidst the spectacular Agrafa Mountains, as well as the unspoilt villages of Mesenikolas and Bezoula, the Smokovo and Kaitsa spas, the Mycenean era tombs outside Georgiko and a multitude of ancient and Byzantine monuments scattered throughout the prefecture.